The Cell Expansion Market is estimated for 2023-2030 for the forecast period, as highlighted in a new report published by Coherent Market Insights.
Market Overview:
Cell expansion is the process by which cells are derived from stem cells extracted from the body and grown into large numbers before being used in transplant medicines, regenerative therapies and drug development research. It has applications in disease modeling, personalized medicine development and cell therapy.
Market Dynamics:
The global cell expansion market is expected to witness significant growth over the forecast period owing to advancements in regenerative medicine and increasing demand for cell-based therapies for chronic diseases. Regenerative medicine aims to regrow or replace damaged tissues and organs. Continued research and development in this domain has expanded the potential for cell-based treatments for diseases like cancer, cardiovascular disorders and neurological conditions. Further, growing geriatric population prone to chronic illnesses will propel the demand for innovative therapies.
Cell Expansion Market Drivers
Increasing prevalence of chronic and infectious diseases
The growing prevalence of chronic and infectious diseases such as cancer, HIV/AIDS, and cardiovascular diseases is one of the major drivers of the global cell expansion market. For instance, according to WHO, cancer is one of the leading causes of death worldwide, with about 10 million new cases reported in 2020. Cell expansion plays a crucial role in the development of new cell therapies to treat such diseases. The growing patient pool diagnosed with chronic illnesses is expected to augment the demand for advanced cell-based therapeutics in the coming years, thereby fueling market growth.
Advancements in regenerative medicine
Rapid advancements in the field of regenerative medicine have enabled the development of novel cell-based therapies using stem cells. Stem cell therapies offer promising treatment outcomes for a wide range of degenerative conditions that currently lack effective therapeutic solutions. Cell expansion is an integral part of stem cell research activities and commercialization of cell therapy products. The development of innovative stem cell therapy approaches for the treatment of retinal degeneration, musculoskeletal disorders, and cardiac diseases is fueling the need for robust cell expansion techniques. This is expected to propel the cell expansion market during the forecast period.
Cell Expansion Market Restrain
High costs associated with cell expansion procedures
While cell expansion proves to be invaluable for advancing the frontiers of modern medicine, the processes involved come with substantial costs. Developing optimized media formulations for particular cell types, single-use bioreactors and consumables, and stringent regulatory compliance all contribute to the high costs. In addition, set-up and maintenance of GMP facilities for cell expansion require huge capital investments. These factors make the overall cell expansion procedures cost-prohibitive for small biotech companies and academic institutes. The high commercialization costs pose a major challenge to market growth, especially in price-sensitive developing regions.
Cell Expansion Market Opportunity
Increasing commercialization of cell therapies
The approval and launch of the first few commercial cell therapies in recent years have generated huge optimism around the clinical and commercial potential of this novel therapeutic modality. For example, Kymriah and Yescarta received FDA approval for the treatment of certain types of leukemia and lymphoma in 2017. Novartis has also received approval to market Kymriah in Europe. These commercial approvals validate the promise of cell therapies and serve as proof of concept for the market. With numerous cell therapy candidates in late-stage clinical trials, the commercialization of new cell-based products is expected to gather strong momentum in the foreseeable future. This growing commercial acceptance presents lucrative opportunities for cell expansion solution providers.
Cell Expansion Market Trends
Adoption of automated and closed cell expansion systems
Biopharmaceutical firms and research institutes are demonstrating rising preference for automated and closed cell expansion systems over conventional plasticware-based methods. Automated platforms help achieve higher cell yields in a more reproducible and contamination-free manner. Closed bioprocessing also ensures sterility and process integrity during cell amplification processes. Major players are continuously innovating and commercializing novel automated and closed cell expansion technologies like miniature bioreactors. This shift from open to closed automated systems is a key trend that is expected to positively impact the trajectories of technology providers. It will further augment the applications of cell expansion in industrial bioprocessing in the long run.
